MushMaps
2020-11-17

MDMA

Substance Abuse

Anxiety

Stress

MDMA is a synthetic drug that is chemically similar to both stimulants and psychedelics. It was originally created as a life-saving blood-clotting medicine, which was first synthesized in 1912 by Dr. Anton K’llisch for the German pharmaceutical company Merck. However, significant testing was not done until 1927, after chemist Max Oberlin determined that it could mimic adrenaline since the two compounds shared a similar structure. Unfortunately, testing was put on hold due to a rise in price of chemical precursors. MDMA was not revived again until the mid-1970s, when American psychopharmacologist Alexander ‘Sasha’ Shulgin, who discovered nearly 250 psychedelic drugs and was famously known as ‘the Godfather of Ecstasy,’ synthesized MDMA and tested it on himself. Impressed with the experience, Shulgin recommended it to therapists and psychiatrists, including psychotherapist Dr. Leo Zeff, who introduced it to over 4,000 patients. The work of Alexander ‘Sasha’ Shulgin cannot be understated as he was a brilliant organic chemist and truly fearless psychonaut who was able to theorize and synthesize these chemicals (built on the frameworks of tryptamines and phenethylamines) and experiment with them at low doses until a perception shift was achieved.

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