Providing Unbiased & Inclusive Information from the Entire Industry
How Do We Make Sense of DMT Realms?
Many people who try DMT report encounters with otherworldly spiritsÑbut what do they mean? A journalist explores.
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79% of Canadians Support Psilocybin To Treat Existential Dread for End of Life Patients | High Times
Researchers also asked survey participants about their opinions on whether psilocybin should be covered by the countryÕs public health system, and if they support legalization.
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European Union Grants Û6.5M for Multi-Site Psilocybin Study in Palliative Patients – Psychedelic Alpha
The European Union has awarded Û6.5 million to support a multi-site randomised controlled trial of psilocybin to ease psychological and existential distress in a variety of progressive illnesses likeÉ
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APPAÕs Stephen Xenakis Discusses the Future of Psychedelic Therapy – Lucid News
The executive director of the American Psychedelic Practitioners Association shares his vision for the professionalization of psychedelic-assisted therapy, as FDA approval seems likely this year.
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MDMA-assisted psychotherapy for PTSD: Growing evidence for memory effects mediating treatment efficacy – PubMed
The application of MDMA in conjunction with psychotherapy has in recent years seen a resurgence of clinical, scientific, and public interest in the treatment of posttraumatic stress disorder (PTSD). Clinical...
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Landmark Study Highlights Efficacy of MDMA-Assisted Therapy for PTSD
In a first of its kind study, MDMA-assisted therapy successfully supported patients with PTSD.
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California Lawmakers Approve Bill To Create Psychedelics Workgroup And Prepare For Legal Therapeutic Access – Marijuana Moment
A California Assembly committee has unanimously approved a revised bill to create a state workgroup that would be tasked with exploring a regulatory framework to provide therapeutic access to psychedelics...
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The Obscure Advisory Panel Blocking Dozens of Psychedelic Studies in California – Psychedelic Alpha
Dozens of new psychedelics studies are unable to commence in California, despite having clearance from the likes of the FDA and DEA. The backlog is costing millions of dollars and...
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100 Grassroots Psychedelic Community Leaders You Need to Know in 2024
We compiled a nice list, so now they can't say "We didn't know".
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Life, death and zombie mushrooms: in search of the AmazonÕs rarest fungi | Fungi | The Guardian
Mycologists Alan Rockefeller and Mandie Quark are on a mission to meticulously document species in EcuadorÕs jungle Ð before they vanish
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VA Is Funding New Research On Psychedelics’ Benefits For Veterans With PTSD And Depression – Marijuana Moment
In a major milestone on the path to expanding access to psychedelic-assisted therapy among the nationÕs military veterans, the Department of Veterans Affairs (VA) has issued a request for applications...
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Psychedelic Ibogaine Can Help Relieve PTSD, Depression: What to Know
A new study finds a type of psychedelic called ibogaine may help people with traumatic brain injury. In the study 30 male Special Operations Forces veterans with traumatic brain injury...
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Were the monks on drugs? How The Book of Kells went fully psychedelic | Art | The Guardian
Spirited to Ireland to save it from the Vikings, this wild illumination of the New Testament, full of gilded curls and coils, is one of the most ecstatic artworks ever...
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AMA Rolls Out New Psychedelic Therapy Codes as FDA Mulls Over Prescription MDMA | High Times
The American Medical Association codes aim to standardize psychedelic treatments and provide coverage and reimbursement.
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New American Medical Association Psychedelic Therapy Codes Take Effect As FDA Weighs Prescription MDMA Application – Marijuana Moment
As the Food and Drug Administration (FDA) considers an application to approve MDMA as a prescription drug, new standards from the American Medical Association (AMA) have officially taken effect that...
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Research Suggests Psilocybin Group Therapy Holds Promise for Treating Depressed Cancer Patients – PsychedelicNewsWire (PNW)
A study published in the American Cancer SocietyÕs peer-reviewed ÒCANCERÓ journal has revealed that psilocybin-assisted group therapy may help treat depression in cancer patients. Psilocybin is one of several classic...
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Psilocybin Could Significantly Help This Much-Understudied Condition
Many researchers view psychedelic medicine as a promising avenue for eating disorders, and preliminary results are encouraging.
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No, DMT Aliens ArenÕt Real
Hate to break it to you, but the deities you encounter in the DMT dimension are figments created by your brain.
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New research explores the relationship between spiritual well-being and psychedelic use
A study in Brazil examines the spiritual well-being of psychedelic users and non-users, revealing distinct experiences and emphasizing the need for inclusive spirituality assessment tools.
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Psilocybin Spores: Where to Buy Mushroom Spores
Psilocybin spores are technically legal, but in most places, germinating them is not.
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Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
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Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
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Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
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Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
Read More
Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
Read More
Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
Read More
Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
Read More
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
Read More
Popular News
Psilocybin’s anxiety-reducing effects linked to stress hormone spike, ...
A recent study in ACS Pharmacology & Translational Science discovered that a temporary spike in stress hormones, specifically corticosterone, plays... Read More
Can Psilocybin Stimulate Neurogenesis in the Hippocampus? | Psychology Toda ...
Hippocampal neurogenesis may play a role in psilocybin's antidepressant action. Read More
The Former Pro Athletes Turning to Magic Mushrooms for Relief
The use of psychedelic mushrooms is gaining traction in the United States. Many researchers predict FDA approval of a psychedelic... Read More
Psychedelic Drugs Are Moving From The Fringes Of Medicine To The Mainstream
Psychedelic agents are experiencing a veritable renaissance. In recent years a slew of psychedelic agents have filled the drug development... Read More
Meet Rhoney Stanley, Underground LSD Chemist behind the 60s Psychedelic Rev ...
Countless women from the first psychedelic revolution never got their dueÑRhoney Stanley is one of them. Read More
400 years ago, visitors to this painted cave took hallucinogens
People at CaliforniaÕs Pinwheel Cave left evidence of their altered state literally stuffed into its wallsÑthe first physical evidence for... Read More