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Psilocybin Spores: Where to Buy Mushroom Spores
Psilocybin spores are technically legal, but in most places, germinating them is not.
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Psilocybin-assisted group therapy might produce clinically meaningful reductions in depression in cancer patients
Psilocybin-assisted group therapy might help reduce depression in cancer patients. This innovative approach, blending psychedelic effects with psychological support, has demonstrated promising results in improving mental health and quality of...
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Shrooms Helped Them Quit Booze and Fentanyl. Now TheyÕre Fighting for Legal Access.
Canadians are suing the federal government for medical access to psychedelic mushrooms.
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Congress Approves Defense Bill Funding Psychedelic Research | High Times
Congress has passed a defense spending bill that includes $10 million to fund research into psychedelics to treat active duty service members with traumatic brain injuries or PTSD.
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Psilocybin-assisted group therapy in patients with cancer diagnosed with a major depressive disorder
Depression is common in patients with cancer and is associated with lower treatment adherence and reduced quality of life. Antidepressants and psychotherapy have limited success in improving depression among patients...
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The Magic Behind the Molecules: Psilocybin vs. Alcohol | Psychology Today
Learn surprising facts about psilocybin, the main ingredient in magic mushrooms.
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Identification of 5-HT2A receptor signaling pathways associated with psychedelic potential | Nature Communications
Serotonin 5-HT2A receptor signaling mechanisms associated with predicting psychedelic potential remain elusive. Using 5-HT2A-selective _-arrestin-biased ligands, here the authors show that a threshold level of 5-HT2A-Gq efficacy and not _-arrestin...
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Congress Sends Biden Defense Bill That Would Fund Studies Into Psychedelics Therapy For Active Duty Military – Marijuana Moment
A large-scale defense bill that contains provisions to fund studies into the therapeutic use of psychedelics such as psilocybin and MDMA for military service members is officially heading to President...
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Top 2023 Psychedelic Studies Reveal Optimal Psilocybin Doses for Depression | Psychedelic Spotlight
2023 psychedelic research shows optimal psilocybin dose for depression and the efficacy of psilocybin to treat depression.
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MDMA Therapy for PTSD Inches Closer to FDA Approval
The FDA will have 60 days "to determine whether the MDMA-AT NDA application will be accepted for review and whether it will be a priority or standard
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FDA Receives NDA From MAPS PBC Regarding MDMA-Assisted Therapy For PTSD – The Dales Report
MAPS PBC has formally submitted a New Drug Application (NDA) to the FDA for MDMA (capsules) in conjunction with MDMA-assisted therapy
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FDA Weighs New Application To Approve MDMA As First-Ever Psychedelic Medicine For PTSD – Marijuana Moment
A psychedelics-focused drug development company is officially asking the Food and Drug Administration (FDA) to review an application to approve MDMA as a prescription medication for the treatment of post-traumatic...
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BREAKING: MAPS PBC Files New Drug Application for MDMA-Assisted Therapy for PTSD – Psychedelic Alpha
MDMA-assisted therapy becomes the first psychedelic therapy submitted to the FDA for approval. Here, we look at what happens next.
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Why Do Magic Mushrooms Bruise Blue? Mystery Solved
The blue coloration of magic mushrooms is a chemical reaction triggered by damage or stress. This process, similar to how an apple turns brown when cu
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Psilocybin’s ‘Efficacy And Safety’ For Bipolar II Depression Demonstrated By American Medical Association Study – Marijuana Moment
Results of a new clinical trial published by the American Medical Association Òsuggest efficacy and safetyÓ of psilocybin-assisted psychotherapy for treatment of bipolar II disorder, a mental health condition often...
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5 Legal Ways to Explore Psychedelic Experiences
Delving into 5 legal ways to explore psychedelic experiences, and the potential risks of using these hallucinogenic substances.
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Single-Dose Synthetic Psilocybin With Psychotherapy for Treatment-Resistant Bipolar Type II Major Depressive Episodes: A Nonrandomized Controlled Trial | Bipolar and Related Disorders | JAMA Psychiatry | JAMA Network
This open-label nonrandomized controlled trial evaluates the safety and efficacy of single-dose psilocybin with psychotherapy for depressive episodes in individuals with bipolar disorder.
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Developing a Direct Observation Measure of Therapeutic Connection in Psilocybin-Assisted Therapy: A Feasibility Study – PubMed
Context: Measuring therapeutic connection during psilocybin-assisted therapy is essential to understand underlying mechanisms, inform training, and guide quality improvement. Purpose: To evaluate the feasibility of directly observing indicators of therapeutic...
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Psychiatry Expert: Paving a Pathway to Psilocybin Legalization
The exploration of psilocybin's potential as a therapeutic agent represents a promising pathway for individuals grappling with treatment-resistant psychiatric disorders.
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Benefits of psychedelics: Can they teach us about the search for meaning in life? – Vox
Everything seems profound on psychedelics. Scientists are starting to ask why.
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Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
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Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
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Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
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Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
Read More
Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
Read More
Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
Read More
Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
Read More
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
Read More
Popular News
Oregon becomes first state to legalize psychedelic mushrooms – oregon ...
Oregon will become the first state in the country to legalize psilocybin with the passage of Measure 109. Read More
How to Change Your Mind: the documentary that wants you to think again abou ...
NetflixÕs weighty new show follows thumpingly authoritative author Michael Pollan as he outlines the benefits of psychedelic drugs such as... Read More
Watch: THC Kills Cancer Cells – Sociedelic
This article originally appeared on Cannabis Now. THC has a miraculous capacity to help those who suffer from cancer. The... Read More
Developing a Direct Observation Measure of Therapeutic Connection in Psiloc ...
Context: Measuring therapeutic connection during psilocybin-assisted therapy is essential to understand underlying mechanisms, inform training, and guide quality improvement. Purpose:... Read More
Feds Fund Study Into Whether Psilocybin Can Help People Quit Smoking Cigare ...
A top federal drug agency is funding a study into how psilocybin could help people quit smoking cigarettesÑone of the... Read More
Couples Are Doing MDMA and Ketamine Therapy To Save Their Relationships
From breaking harmful patterns to improving their sex lives, more couples are using psychedelics combined with therapy to confront their... Read More