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A Psychedelics Boom Is Minting Environmentalists
Proponents of a new wave of interest in hallucinogens say the right trip at the right time can change how people think about the natural world.
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Stacking Psychedelic Microdoses with ADHD Medication? | Psychedelic Spotlight
A new study exploring real-world psychedelic microdosing for ADHD could help reimagine the way we perceive and treat the condition.
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Bringing Psychedelic Healing to Queer and Trans Communities – Lucid News
Despite the victories of the LGBTQIA+ community in recent decades, the need for trauma-informed healing is increasingly urgent, as people grapple with internalized stigma, chronic oppression, homophobia, and rejection.
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Study: Cannabis Elicits Psychedelic Effects in Specific Circumstances | High Times
Is cannabis a psychedelic? This study published in the Journal of Psychopharmacology thinks so.
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Harming While Healing?: The Oppressive Nature of Psychedelic-Centric Drug Policy | Psychedelics Today
The NMHA and other psychedelic initiatives unfortunately do nothing to alleviate the most malignant symptoms of the disease that is the War on Drugs and the categorization of "good drugs"...
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Study Finds That Ayahuasca Could Make You Less Narcissistic | High Times
Narcissists can take a hike. Or maybe a trip.
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Spiritual Well-Being Among Users and Non-Users of Psychedelics: A Cross-Sectional Study
This study evaluated the psychometric properties of the Spiritual Well-Being Scale (SWBS) in a Brazilian sample. We analyzed spiritual well-being, defined as existential well-being (EWB) and religious well-being (RWB), among...
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The psychedelic effects of cannabis: A review of the literature – PubMed
Cannabis and classic psychedelics are controlled substances with emerging evidence of efficacy in the treatment of a variety of psychiatric illnesses. Cannabis has largely not been regarded as having psychedelic...
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Is Ibogaine & 5-MeO-DMT the ultimate 1-2 punch for PTSD?
The potential benefits of combined ibogaine & 5-MeO-DMT assisted therapy include, significant and very large improvements in self reported symptoms of
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Neuroscience research shows psychedelics plus psychotherapy can trigger rapid brain changes
Neuroscience research shows that the brain changes slowly through effortful learning, but can also rapidly rewire during transformative experiences, like those induced by psychedelic-assisted psychotherapy, which leverages a natural neural...
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An Ambitious Vision Drives KentuckyÕs Ibogaine Plan to Treat Opioid Dependency – Lucid News
A Kentucky commission will soon vote on whether to commit $42 million toward a psychedelic-assisted therapy moonshot that could transform treatment for opioid use disorder nationally.
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Veteran Access To Psychedelics Requires Balance Of Speed And Caution, Says Panel With VA And Former CDC Officials – Marijuana Moment
Experts and advocatesÑincluding a Department of Veterans Affairs (VA) official and a former director of the Centers for Disease Control and Prevention (CDC)Ñrecently convened for a Harvard University panel to...
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75 Influential, Innovative, and Disruptive Women in Psychedelics
Take a journey with us as we explore the future of the psychedelics community.
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LSD and psilocybin for chronic nociplastic pain: A narrative review of the literature supporting the use of classic psychedelic agents in chronic pain
Healthcare providers face the challenging task of managing patients who suffer from chronic nociplastic pain conditions. Pain is a multidimensional experience, and the current approach to managing people in chronic...
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Psychedelics Show Potential to Improve SUD Treatment Outcomes
With more than 106,000 drug overdose deaths reported in the US in 2021 and more than 46 million people over the age of 12 having a past-year substance use disorder...
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Protecting the Wild in Plant Medicine: Why Commodification Thwarts Collective Transformation – Third Wave
Ayahuasca's journey from sacred ceremony to global market commodity. It's not just a transaction. It's a conversation.
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Advocates File California Ballot Initiative To Legalize Psychedelics For Medical, Therapeutic And Spiritual Use In 2024 – Marijuana Moment
Advocates in California filed a ballot initiative with state officials on Friday that would create a right Òto obtain and use psychedelics for medical, therapeutic and spiritual purposesÓ with the...
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Psychological and physiological effects of extended DMT – PubMed
N,N-Dimethyltryptamine (DMT) is a serotonergic psychedelic that induces a rapid and transient altered state of consciousness when inhaled or injected via bolus administration. Its marked and novel subjective effects make...
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First Shroom Cultivation License in New Zealand Granted to M_ori Group | High Times
Research in New Zealand will uncover if psilocybin is useful in battling conditions like addiction.
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Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
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Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
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Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
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Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
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Psilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
Read More
Psilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
Read More
Psilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
Read More
Biosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
Read More
Pilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
Read More
Popular News
Children and Psychedelics: Using Indigenous Wisdom to Examine Western Parad ...
For Westerners, the topic of children and psychedelics is a near-untouchable one, mired in taboo and stigma. Many find the... Read More
Research on Psychedelics, Marijuana as Alternative Treatment for Vets Advan ...
Psychedelic drugs and marijuana could be evaluated as treatments for post-traumatic disorder and other conditions afflicting veterans under bills advancing... Read More
Social and Economic Benefits of the Legalization of Psychedelics | Microdos ...
There is increasing evidence that the legalization of psychedelics could have significant economic and social benefits. Read More
Magic Mushrooms. LSD. Ketamine. The Drugs That Power Silicon Valley. – ...
Entrepreneurs including Elon Musk and Sergey Brin are part of a psychedelic movement that proponents hope will expand minds, enhance... Read More
Pushing Back on the Term “Therapy” in Oregon’s Measure 10 ...
As the legislation which created a regulated network for supervised adult psilocybin usage rolls out, conversations on the costs of... Read More
Johns Hopkins University Announces Nation’s First-Ever Psychedelics R ...
A major U.S. university announced on Wednesday that it will be launching the nationÕs first center devoted exclusively to researching... Read More