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The Dales Report
Steve Cohen Bets Again On Biopharma With Purchase Of 119M+ Bionomics Shares – The Dales Report
NY Mets owner billionaire Steve Cohen has bought many ordinary shares of clinical-stage biopharmaceutical company Bionomics Limited
Read MoreMexico News Daily
The legal status of psilocybin in Mexico and the world
As scientific research continues to shed light on the medicinal properties of psilocybin, its legal status has become of interest.
Read MoreGolfDigest.com
Why serious players are dosing psychedelics like mushrooms and ayahuasca | Golf News and Tour Information | GolfDigest.com
Can taking mushrooms help your golf game?
Read MoreHealth Affairs
Exploring Regulatory Frameworks For Psychedelic Services To Treat Mental Illnesses
Mental illnesses are associated with significant morbidity and mortality. Although more Americans are engaging in mental health care, many people living with a mental illness do not receive treatment. Those...
Read MoreHigh Times
Gov. Newsom Signs Bill Allowing MDMA, Psilocybin Prescriptions If/When Feds Reschedule | High Times
The Governor of California has several bills waiting for his signature related to cannabis and psychedelic drugs, two of which were signed into law on Saturday.
Read MoreMarijuana Moment
Maine’s Biggest City Passes Legislation To Decriminalize Psychedelic Plants And Fungi – Marijuana Moment
The City Council in Portland, Maine, has voted to deprioritize the local enforcement of laws against psychedelic plants and fungi, adopting a resolution on Monday that emphasizes treating the use...
Read MorePsychology Today
The Role of the Therapist in Psychedelic Therapy | Psychology Today
The importance of trust.
Read MoreBenzinga
Psyched: DMT & SSRIs For Depression, MDMA Training, Negative Responses To Psychedelics & More – ATAI Life Sciences (NASDAQ:ATAI), Compass Pathways (NASDAQ:CMPS) – Benzinga
Depression Relief: Possible Therapy Boost With DMT & SSRIs Small Pharma Clinical Results New findings on safety, tolerability and efficacy from a clinical study assessing the interaction of psychedelics and traditional...
Read MorePsychedelic Spotlight
Survey Finds Psychiatrists Increasingly Supportive of Psychedelics
Psychiatrists in 2023 are much more optimistic about psychedelic-assisted therapy than they were in 2016
Read MoreSocietyÕs Writer
Understanding Psilocybin in Addiction Recovery: A Comprehensive Analysis Ð SocietyÕs Writer
This article provides a thorough and insightful examination of the role of psilocybin in addiction recovery, drawing on a wealth of research and evidence. It effectively highlights the potential beÉ
Read MorePsychedelic Spotlight
Why Accessible Psychedelic Education in Important
Accessible psychedelic education goes beyond disseminating facts; it fosters open and non-judgmental dialogue. Creating safe spaces for discussion all
Read MoreMarijuana Moment
Federal Officials Talk Psychedelics Research Challenges At Workshop Hosted By Top Health Agency – Marijuana Moment
At a U.S. Department of Health and Human Services (HHS) workshop about psychedelic medicine earlier this month, the director of mental health for the Department of Veterans Affairs (VA) said...
Read MoreNature
Mechanisms and molecular targets surrounding the potential therapeutic effects of psychedelics | Molecular Psychiatry
Psychedelics, also known as classical hallucinogens, have been investigated for decades due to their potential therapeutic effects in the treatment of neuropsychiatric and substance use disorders. The results from clinical...
Read MoreNature
Neuroimaging in psychedelic drug development: past, present, and future | Molecular Psychiatry
Psychedelic therapy (PT) is an emerging paradigm with great transdiagnostic potential for treating psychiatric disorders, including depression, addiction, post-traumatic stress disorder, and potentially others. ÔClassicÕ serotonergic psychedelics, such as psilocybin...
Read MorePsychedelic Spotlight
Zen and Psychedelics Documentary Follows Monks on Mushrooms
"Descending the Mountain" is one of the best documentaries about psychedelics since "Fantastic Fungi."
Read MorePsyPost
New study highlights psilocybin’s promise for major depressive disorder treatment
A recent multi-site study published in the Journal of the American Medical Association revealed that psilocybin-assisted therapy offers rapid and sustained antidepressant effects for individuals with major depressive disorder. Compared...
Read MoreMarijuana Moment
Survey Of Psychiatrists Shows ‘Striking Positive Shift’ In Attitudes Toward Psychedelics Over Past 7 Years – Marijuana Moment
More than 80 percent of surveyed psychiatrists now hold strong to moderate beliefs that psychedelics have potential to treat mental health disorders, according to a newly published study. Compared to...
Read MoreEverydayHealth.com
What Is Psilocybin Therapy? Risks, Benefits, and What to Expect
Explore the potential of psilocybin therapy for treating mental health conditions like depression, anxiety, and substance use disorders. Learn about its history, how it works, benefits, risks, and more.
Read MorePsyPost
Psilocybin might be effective for treatment-resistant depression even with ongoing SSRI use, study suggests
In a phase II clinical trial, a single dose of psilocybin, combined with SSRI treatment and supportive therapy, showed promising safety and therapeutic outcomes for individuals with treatment-resistant depression. While...
Read MorePsilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
Read MorePsilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
Read MorePsilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
Read MoreBiosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
Read MorePilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
Read MorePsilocybin Treatment for Major Depression Effective for Up to a Year for Mo ...
Previous studies by Johns Hopkins Medicine researchers showed that psychedelic treatment with psilocybin relieved major depressive disorder symptoms in adults for up to a month. Now, in a follow-up study of those participants, the researchers report that the substantial antidepressant effects of psilocybin-assisted therapy, given with supportive psychotherapy, may last at least a year for some patients.
Read MorePsilocybin Ð Summary of knowledge and new perspectives – ScienceDire ...
Psilocybin, a psychoactive alkaloid contained in hallucinogenic mushrooms, is nowadays given a lot of attention in the scientific community as a reseaÉ
Read MorePsilocybe Cubensis and Other Types of Magic Mushrooms You Should Know ̵ ...
Magic mushrooms are so incredible and mysterious, from the beautiful experiences they occasion to the mystical compounds that they naturally produce. But
Read MoreBiosynthesis and Extracellular Concentrations of N,N-dimethyltryptamine (DM ...
N,N-dimethyltryptamine (DMT), a psychedelic compound identified endogenously in mammals, is biosynthesized by aromatic-L-amino acid decarboxylase (AADC) and indolethylamine-N-methyltransferase (INMT). Whether DMT is biosynthesized in the mammalian brain is unknown. We investigated brain expression of INMT transcript in rats and humans, co-expression of INMT and AADC mRNA in rat brain and periphery, and brain concentrations of DMT in rats. INMT transcripts were identified in the cerebral cortex, pineal gland, and choroid plexus of both rats and humans via in situ hybridization. Notably, INMT mRNA was colocalized with AADC transcript in rat brain tissues, in contrast to rat peripheral tissues where there existed little overlapping expression of INMT with AADC transcripts. Additionally, extracellular concentrations of DMT in the cerebral cortex of normal behaving rats, with or without the pineal gland, were similar to those of canonical monoamine neurotransmitters including serotonin. A significant increase of DMT levels in the rat visual cortex was observed following induction of experimental cardiac arrest, a finding independent of an intact pineal gland. These results show for the first time that the rat brain is capable of synthesizing and releasing DMT at concentrations comparable to known monoamine neurotransmitters and raise the possibility that this phenomenon may occur similarly in human brains.
Read MorePilot Study of Psilocybin Treatment for Anxiety in Patients With Advanced-S ...
Researchers conducted extensive investigations of hallucinogens in the 1950s and 1960s. By the early 1970s, however, political and cultural pressures forced the cessation of all projects. This investigation reexamines a potentially promising clinical application of hallucinogens in the…
Read More