Psilocybin shows promise in OCD treatment – even without the psychedelic “trip”

Blocking the subjective psychedelic effects of psilocybin does not appear to interfere with the substance’s ability to potentially help with obsessive behaviors, according to new research published in Translational Psychiatry. The findings contribute to the growing body of research on the clinical application of psychedelics in psychiatry and highlight the need for further investigation in clinical trials to evaluate the efficacy and safety of psilocybin in the treatment of obsessive-compulsive disorder (OCD).